"Using the internet to develop and evaluate tinnitus treatments"
Gerhard Andersson, Ph.D. is a professor of Clinical Psychology in the Department of Behavioural Sciences and Learning at Linköping University. He has also been a guest professor at Karolinska Institutet, Stockholm (2007-2012) in the Department of Clinical Neuroscience, Psychiatry (section for Internet Psychiatry), and now continues as an affiliated professor. His clinical work is mainly devoted to audiology, and he has a part-time position as a Clinical Psychologist in the Tinnitus team at the Department of Audiology, Linköping University Hospital. Professor Andersson received his M.Sc. in Clinical Psychology from Uppsala University in 1991. His first Ph.D. was in Clinical Psychology (1995), and his second Ph.D. was in Medicine (2000). He has also completed a B.A. in Theology (2010). Professor Andersson has published over 420 research papers and 15 books, and his research interests include: 1) Cognitive behavioural treatment and psychotherapy, 2) the biological mechanisms, epidemiology and psychological aspects of tinnitus and hearing loss, and 3) using the internet to provide guided psychological treatment.
"The association between tinnitus and hyperacusis: causal, indirect, or coincidence?"
David Baguley is Head of Service: Audiology/Hearing Implants at Cambridge University Hospitals, UK. His initial studies were at the University of Manchester in Psychology (BSc 1980-1983) and then Clinical Audiology (MSc 1984). David has worked in Audiology at Addenbrooke's Hospital since 1985, becoming the Consultant Clinical Scientist in 1989. He has over 140 peer-review publications, and a PhD on the subject of tinnitus from the University of Cambridge (2005). He is a co-author on the books: 'Tinnitus: a multidisciplinary approach' (second edition, Wiley, 2013) and 'Hyperacusis' (Plural, 2007) and co-edited the latest edition of Ballantyne's Deafness (2009) with John Graham. In 2006 David received an International Award in Hearing from the American Academy of Audiology, and has twice been awarded the Shapiro Prize from the British Tinnitus Association for tinnitus research (2005, 2008). He is a Visiting Professor at Anglia Ruskin University. David's clinical and research interests focus upon tinnitus and hyperacusis, with the aim of understanding these symptoms and designing and evaluating novel and innovative interventions.
"Dynamic causal modelling of the auditory system"
Professor Karl Friston is a theoretical neuroscientist and authority on brain imaging. He is the Scientific Director of the Wellcome Trust Centre for Neuroimaging at University College London. He invented statistical parametric mapping (SPM), voxel-based morphometry (VBM) and dynamic causal modelling (DCM). These contributions were motivated by schizophrenia research and theoretical studies of value-learning – formulated as the dysconnection hypothesis of schizophrenia. Mathematical contributions include variational Laplacian procedures and generalized filtering for hierarchical Bayesian model inversion. Professor Friston currently works on models of functional integration in the human brain and the principles that underlie neuronal interactions. His main contribution to theoretical neurobiology is a free-energy principle for action and perception (active inference). He received the first Young Investigators Award in Human Brain Mapping (1996) and was elected a Fellow of the Academy of Medical Sciences (1999). In 2000 he was President of the international Organization of Human Brain Mapping. In 2003 he was awarded the Minerva Golden Brain Award and was elected a Fellow of the Royal Society in 2006. In 2008 he received a Medal, Collège de France and an Honorary Doctorate from the University of York in 2011. He became of Fellow of the Society of Biology in 2012, received the Weldon Memorial prize and Medal in 2013 for contributions to mathematical biology and was elected as a member of EMBO (excellence in the life sciences) in 2014.
"Cochlear synaptopathy - a possible role in the generation of tinnitus"
M. Charles Liberman, Ph.D. is the Schuknecht Professor of Otology and Laryngology at the Harvard Medical School and the Director of the Eaton-Peabody Laboratories at the Massachusetts Eye and Ear Infirmary, one of the largest and best-known research groups devoted to the study of hearing and deafness. The laboratory comprises 27 investigators, with research foci spanning all aspects of the auditory system from sound transmission in the middle ear, through signal transduction in the inner ear and neural processing in the central nervous system. Dr Liberman received his B.A. in Biology from Harvard College in 1972 and his Ph.D. in Physiology from Harvard Medical School in 1976. He has been on the faculty at Harvard since 1979, has published over 150 papers on a variety of topics in auditory neuroscience and is the recipient of the Award of Merit from the Association for Research in Otolaryngology, the Carhart Award from the American Auditory Society and Bekesy Silver Medal from the Acoustical Society of America. His research interests include 1) coding of acoustic stimuli as neural responses, 2) efferent feedback control of the auditory periphery, 3) mechanisms underlying noise-induced hearing loss, 4) the signaling pathways mediating nerve survival in the inner ear and 5) application of cell- and drug-based therapies to the repair of a damaged inner ear.
"Frontostriatal Dysfunction in Chronic Tinnitus"
Josef P. Rauschecker studied at TUM and LMU Munich (Electrical Engineering and Medicine) and at the Universities of Sussex and Cambridge, England (Artificial Intelligence and Physiology). He received his Ph.D. from TUM in 1980 for work performed at the Max Planck Institute (MPI) for Psychiatry in Munich and his habilitation (D.Sc.) for Neurophysiology in 1985 at Eberhard Karls University Tübingen. After working as Staff Scientist at the MPI for Biological Cybernetics from 1981-1989, he joined the National Institute of Mental Health (USA) as Senior Investigator in the Laboratories of Neuropsychology and Neurophysiology in 1989. Since 1995, he has been a Professor of Physiology and Biophysics, Neurology, and Neuroscience at Georgetown University, where he is also Director of the Laboratory of Integrative Neuroscience and Cognition (LINC) and has served on the university’s Executive Council and on its Steering Committee.
Josef Rauschecker has 35 years of experience in systems and cognitive neuroscience, >25 years of experience in animal electrophysiology, and >15 years of experience with functional magnetic resonance imaging (fMRI). At Georgetown University Medical Center, he helped create the first human fMRI research facility and participated in the implementation of the first 7-Tesla small-animal MRI. He has numerous pertinent publications in peer-reviewed journals and has been the mentor of >30 graduate students and postdoctoral fellows. Josef P. Rauschecker’s research is funded by the National Institutes of Health (USA) and the National Science Foundation (USA). He has also held visiting appointments at several institutions, including Harvard Medical School, Rockefeller University, The Salk Institute, and Aalto University. He has been the recipient of a Humboldt Award and a Finland Distinguished Professorship and is currently Hans-Fischer Senior Fellow at the Institute for Advanced Study at TU Munich.
"Towards a better understanding of tinnitus heterogeneity"
Winfried Schlee (born in 1978) is a German neuropsychologist at the University of Regensburg. He studied psychology, statistics and philosophy at the University of Konstanz and the University of Alabama at Birmingham. In 2009 he obtained his PhD in clinical neuropsychology at Konstanz where he introduced the concept of the Global Model of Tinnitus Perception to explain the neuronal mechanisms underlying the conscious perception of the tinnitus percept. Since then, Dr Schlee has studied various factors influencing the conscious perception of tinnitus, among them the influence of age, stress and emotional arousal, the interference with auditory, electric and magnetic stimulations, as well as intrinsic neuronal moment-to-moment fluctuations of the resting alpha activity in temporal brain regions. In 2013, he joined the Tinnitus Research Initiative (TRI) where his current work focuses on discovering new methods for the treatment and measurement of chronic tinnitus. He is also chair of the European COST project "TINNET - Better understanding the tinnitus heterogeneity to improve and develop new treatments", which started in April 2014.
"Mechanisms of tinnitus initiation in the cochlear nucleus"
Professor Shore received her B.A. in Speech Pathology and Audiology and her M.A. in Hearing Science (Cum Laude) in the Department of Speech Pathology and Audiology, University of Witwatersrand, Johannesburg, South Africa. She received her Ph.D. in Physiology at the Kresge Hearing Research Laboratory of the South in New Orleans, Louisiana. Postdoctoral studies were conducted at the University of Pittsburgh and Kresge Hearing Research Institute, University of Michigan Medical School. Currently, Dr Shore is a Professor of Otolaryngology, Molecular and Integrative Physiology and Biomedical Engineering at the University of Michigan in Ann Arbor, Michigan. She also holds the Joseph Hawkins Collegiate Research Professorship at the University of Michigan.
Professor Shore’s laboratory studies the contributions of multisensory systems to auditory processing and discovered that ‘touch-sensitive’ neurons in the brain, that receive input from the face and head, send neural projections to the auditory brainstem. Most remarkably, after unilateral deafness, there is a strong enhancement in somatosensory influences on the cochlear nucleus, as if in compensation for the loss of input from the cochlea. Furthermore, in animals with tinnitus, there is increased excitation from the somatosensory system (http://www.uofmhealth.org/news/tinnitus-kresge-0201). Work extending these findings is now focused on stimulus-timing dependent synaptic plasticity as an underlying mechanism to explain the long-term nature of these changes (http://www.uofmhealth.org/news/archive/201312/u-m-tinnitus-discovery-opens-door-possible-new-treatment). Ongoing work is laying the groundwork for treatments that include specific, patterned stimulation that may ‘reverse’ the increased excitation that contributes to tinnitus.
"The TRI database: Big data as a chance to improve clinical characterisation and development of new treatments for tinnitus"
Michael Landgrebe is a senior physician and specialist in psychiatry and psychotherapy at the University of Regensburg, Germany. He received his PhD and doctorate in medicine from the University of Göttingen in 1999 and moved to the University of Regensburg in 2004. He is the co-chair of the TINNET Working Group 2, focusing on standards for data management and analyses.
"Management of Tinnitus in Children – the UK approach"
Dr Veronica Kennedy is an Audiovestibular Physician, based in Bolton, UK, specialising in hearing and balance disorders in children. She has had a long standing interest in tinnitus both in adults and children. She is a member of the TINNET Clinical Outcomes Working Group. As part of the British Society of Audiology multidisciplinary working group, she co-authored national Good Practice Guidance on the assessment and management of tinnitus in children. She is actively involved with the British Tinnitus Association who has developed leaflets and school resources for children with tinnitus.